- Contagious caprine pleuropneumonia (CCPP) is a severe disease affecting goats and some wild ruminant species, caused by the bacteria Mycoplasma capricolum subsp. capripneumoniae (Mccp). In goats it is manifested by anorexia, fever and respiratory signs such as dyspnoea, polypnea, cough and nasal discharges. The acute and subacute disease is characterised by unilateral sero-fibrinous pleuropneumonia with severe pleural effusion. In CCPP outbreaks in mixed goat and sheep herds, sheep may also be infected. CCPP has been confirmed in wild goats (Capra aegagrus), Nubian ibex (Capra ibex nubiana), Laristan mouflon (Ovis orientalis laristanica), gerenuk (Litocranius walleri) and sand gazelle (Gazella marica) with significant morbidity and mortality in these species. In sand gazelle the mortality rate reached up to 70%. There is growing evidence that a number of other wild ruminant species are also susceptible, such as the Tibetan antelope (Pantholops hodgsonii) and Arabian oryx (Oryx leucoryx). Inactivated and adjuvanted CCPP vaccines are available. CCPP is not a zoonotic infection.
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